This course will cover basic principle of skeletal biology which will include:

1) Principle fo bone biology : Part 1 and 2 

2) Biology of the matrix

3) Calcium and Phosphate homeostasis

4) Osteoporosis and Osteopenia

5) Biomechanics of Bone

6) Sclerostin and Wnt signaling pathways

7) Skeletal Mechanobiology

8) Tools to study the skeleton: in vitro and in vivo models

9) Emerging techniques: RNA-seq, single cell RNA-seq, ATAC-seq  and article discussion

10) Course review with Q&A